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There are two cannabinoids derived from hemp, THC-O and Delta-8. Both produce similar effects and have a range of medical and recreational applications; however, they differ in a few important ways.

It is important to note that THC-O and Delta-8 have very different legal statuses when compared to one another. Some states allow THC-O to be used, while others allow Delta-8. However, most states do not allow Delta-8 to be used.

What Is THC-O?

How It Works

This new synthetic cannabinoid is derived from hemp and produces euphoric and psychoactive effects on the user. THC-O is short for tetrahydrocannabinol-o-acetate. Unlike CBD, CBN, and CBG, derived from hemp, THC-O is not naturally found within a hemp plant.

A special type of equipment and acetic anhydride are necessary for synthesizing THC-O. CBD from hemp plants is converted into Delta-8 THC for the production of THC-O through a combination of Delta-8 THC and acetic anhydride. As a final step, unwanted chemicals and solvents are removed from the product.


In contrast to other THC products, THC-O products could potentially carry therapeutic benefits; however, their primary purpose is to be consumed recreationally. Consumers are said to experience mild hallucinogenic or psychedelic effects with THC-O, which may be more potent than THC.

Some users report that THC-O has provided mild visual effects and boosted their mental and spiritual awareness, similar to what they experience with other psychedelics.

What Is Delta-8?

How It Works

In marijuana and hemp, Delta-8 THC (sometimes referred to as “Delta-8”) provides psychoactivity. Although the cannabis plant naturally produces it, it is not found in significant amounts, so hemp-derived cannabidiol is typically used to make it.

The chemical structure of Delta-8 is similar to that of Delta-9 THC, producing a milder high as well as having fewer side effects than Delta-9 THC, the psychoactive ingredient in marijuana that causes a “high.” The chemical structure of Delta-8 is similar to that of Delta-9 THC.


Delta-8 is commonly used for pain relief, nausea relief, and relaxing and producing euphoric feelings. Nevertheless, there has been little research supporting these claims.

In the absence of further research, Delta-8 hasn’t been determined to be more beneficial than dangerous.

The potential benefits

Delta-8 has not been thoroughly researched, so social media is used to report its potential benefits. There has been some suggestion that Delta-8 be used alongside prescription medications to treat depression and substance abuse. Delta-8 has also been reported to have the following effects:

  • Appetite increase
  • Cancer treatment, nausea prevention
  • Reduction of pain
  • A better outlook on life

THC-O and Delta-8: Similarities and Differences

Compared to Delta-8, THC-O produces a borderline hallucinogenic effect, while Delta-8 produces soothing and sedative effects. Both are hemp derivatives and can provide a high to a user.

The Best One for You: How to Decide

THC-O: When to Use It

Recreational uses of THC-O are the most common. Products containing THC-O have been reported to produce almost hallucinogenic or psychedelic effects in users. The best thing to do is to stay away from it.

Delta-8: When to use it

Delta-8 has been used therapeutically for many years. In addition to its anti-anxiety and anti-nausea properties, Delta-8 has a low potency that produces less psychoactive effects.

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